The human body follows a particular process when healing itself from injuries. Inflammation causes the blood to clot to avoid bleeding, afterwards, the destruction phase begins whereby the wound gets cleaned of any old cells to prevent infections. The third in the process is proliferation, this is a phase whereby new skin is created by fibroblasts. Maturation is the last phase and its purpose is to bring together the newly formed tissues to close the opening. Now the bruise will be regarded as healed. There are instances where this process fails and healing doesn t occur. Human intervention is then required, GMO skinap wound healing is one backup solution.
Proper blood circulation is very important in the curing process, when blood flow gets destructed, curing slows down. Diabetes and Raynaud s disease are examples of major causes of poor blood circulation that is why people suffering from these diseases often get foot ulcers (non-healing leg bruises). The older the body gets, the slower its nervous system becomes, that is why older people also suffer from non-curing bruises in numbers.
A chronic wound should not be ignored because serious health problems may follow if it catches an infection, the worst that could happen is that doctors may recommend amputation of body parts like legs and feet if they get affected beyond repair. These are the signs of an infected cut; pain intensifies, the area starts to be red and warm, or it overflows with an odourful discharge.
In the olden days, people used organisms like leeches to help with the remedial process. Recently, doctors have taken on that old method and use them together with the latest technology to make it better than before. Genetically modified maggots are used instead of leeches.
Maggots are placed on the affected area where they will clean and remove dead tissues. On top of that, they secrete a liquid that prevents the wound from getting infected, the liquid is often called an antimicrobial secretion. Although the wound finally gets healed, it does so after some time, so maggots don t speed up the healing time. Some doctors, after performing experiments argue that maggots should only be used for debridement, otherwise they will become deleterious to the skin.
So scientists came up with a way of making them (maggots) be able to ignite or promote skin cell growth. They modified them genetically to produce a certain human growth factor called the platelet-derived growth factor-BB (PDGF-BB). They made 2 groups to produce this growth factor under different conditions. The first group only make PDGF-BB when they exposed to a temperature of 37 degrees Celsius.
Then others were made to produce it when they were given a diet that didn t have a certain bacteria called tetracycline. The maggots which used temperature as a factor of producing PDGF-BB failed to emit it out of their bodies and thus are useless.
This new science of using genetically modified organisms for non-healing wounds is used by several companies like Skinap therapeutics. This company has other methods not discussed here.
Proper blood circulation is very important in the curing process, when blood flow gets destructed, curing slows down. Diabetes and Raynaud s disease are examples of major causes of poor blood circulation that is why people suffering from these diseases often get foot ulcers (non-healing leg bruises). The older the body gets, the slower its nervous system becomes, that is why older people also suffer from non-curing bruises in numbers.
A chronic wound should not be ignored because serious health problems may follow if it catches an infection, the worst that could happen is that doctors may recommend amputation of body parts like legs and feet if they get affected beyond repair. These are the signs of an infected cut; pain intensifies, the area starts to be red and warm, or it overflows with an odourful discharge.
In the olden days, people used organisms like leeches to help with the remedial process. Recently, doctors have taken on that old method and use them together with the latest technology to make it better than before. Genetically modified maggots are used instead of leeches.
Maggots are placed on the affected area where they will clean and remove dead tissues. On top of that, they secrete a liquid that prevents the wound from getting infected, the liquid is often called an antimicrobial secretion. Although the wound finally gets healed, it does so after some time, so maggots don t speed up the healing time. Some doctors, after performing experiments argue that maggots should only be used for debridement, otherwise they will become deleterious to the skin.
So scientists came up with a way of making them (maggots) be able to ignite or promote skin cell growth. They modified them genetically to produce a certain human growth factor called the platelet-derived growth factor-BB (PDGF-BB). They made 2 groups to produce this growth factor under different conditions. The first group only make PDGF-BB when they exposed to a temperature of 37 degrees Celsius.
Then others were made to produce it when they were given a diet that didn t have a certain bacteria called tetracycline. The maggots which used temperature as a factor of producing PDGF-BB failed to emit it out of their bodies and thus are useless.
This new science of using genetically modified organisms for non-healing wounds is used by several companies like Skinap therapeutics. This company has other methods not discussed here.
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